About the role
Job | Kyverna Therapeutics Platform & Pipeline Opportunity CAR T-Cell Therapy Pipeline Clinical Trials and Expanded Access Patients Experience Stiff Person Syndrome Myasthenia Gravis Multiple Sclerosis Lupus Nephritis Systemic Sclerosis Inside Kyverna Leadership Mission & Values Education & Events Events Publications Videos Investors News Careers Contact --> ← Back Medical Director/Sr. Medical Director, Clinical Development Remote Clinical Full Time Kyverna Therapeutics is a patient-centered, clinical-stage biopharmaceutical company developing cell therapies for patients suffering from autoimmune diseases. Guided by our core values, Stay True to Why, Collaborate to Accelerate, Lead with Clarity, Boldly Innovative, and Own the Outcome, we are committed to transforming the future of treatment for autoimmune disease. Join us at the forefront of cell therapy innovation and help redefine what’s possible. Title: Medical Director/Sr. Medical Director, Clinical Development Location: Remote or Hybrid Reports To: SVP, Clinical Development & Medical Affairs
Responsibilities Serve as the physician lead for CAR T-cell therapy clinical trials in autoimmune disease indications, in partnership with internal and external cross-functional teams. Oversee medical monitoring of clinical trials, including engagement with site investigators and external medical monitors. Partner with clinical operations, biometrics, regulatory, and commercial teams to ensure alignment on strategy and execution. Lead design, execution, and interpretation of clinical trials across assigned program Provide medical and scientific input into clinical development plans, study protocols, investigator brochures, and regulatory submissions. Medical review, analysis, and interpretation of safety, efficacy, and PK and biomarker data. Development of clinical trial documents including protocols, ICFs, clinical development plans, and publications. Lead the development of clinical sections of regulatory documents including the IB, safety updates, clinical study reports, and responses to Health Authorities. Actively engage with external investigators and researchers to identify, evaluate, and support investigator sponsored studies and drive research collaborations.