About Parabilis Medicines Parabilis Medicines is a clinical-stage biopharmaceutical company dedicated to creating extraordinary medicines for patients with serious diseases by unlocking biologically important targets long considered undruggable. The company has pioneered a new class of alpha-helical peptides – Helicons™ – capable of modulating intracellular proteins that have historically been beyond the reach of conventional medicines. The company’s lead investigational medicine, zolucatetide, is the first and only direct inhibitor of the β-catenin:TCF interaction, a central node in the Wnt/β-catenin pathway that has eluded drug developers for decades. Zolucatetide is being evaluated in the clinic across multiple Wnt/β-catenin-driven diseases, including desmoid tumors, familial adenomatous polyposis (FAP) and a range of other solid tumor indications. Beyond zolucatetide, Parabilis is advancing additional Helicon-based programs focused on other challenging targets where we believe our medicines could have life-altering impact. For more information, visit www.parabilismed.com or follow us on LinkedIn . What’s the opportunity? The Vice President, New Product Planning will play a key strategic leadership role in shaping the development and future direction of Parabilis Medicines’ portfolio. Reporting to the Chief Business & Strategy Officer, this individual will lead New Product Planning activities across the company’s pipeline, ensuring commercial, market, and strategic insights are integrated into critical program decisions throughout development. This leader will partner cross-functionally across Clinical Development, Research, Regulatory, CMC, Business Development, and Executive Leadership to help define product and indication strategies, evaluate market opportunities, assess competitive dynamics, and inform long-term portfolio planning.
The role is particularly critical as Parabilis advances zolucatetide (FOG-001) towards registrational Phase 3 study for desmoid tumor and pursue expansion indications including familial adenomatous polyposis (FAP), adamantinomatous craniopharyngioma (ACP), hepatocellular carcinoma (HCC) and a range of other Wnt/beta-catenin-driven solid tumors. The ideal candidate will bring a strong blend of commercial and marketing experience, strategic thinking, cross-functional leadership, scientific curiosity, and operational pragmatism, along with a passion for helping build innovative biotechnology companies. Build scalable New Product Planning capabilities and processes to support the company’s long-term growth Lead New Product Planning activities for zolucatetide and future pipeline opportunities along with
the team and lead or support future commercial readiness activities including launch preparation frameworks, go-to-market strategy development, and cross-functional alignment on pre-launch milestones and priorities. Partner closely with the Global Program Team and key functional leaders to incorporate commercial and market insights into development strategy, indication prioritization, and lifecycle planning. Assess market opportunities, competitive landscapes, unmet patient needs, and evolving standards of care across oncology and rare disease indications. Help shape product positioning, differentiation, value proposition, pricing considerations, and future market development strategies. Provide strategic commercial input into portfolio prioritization, long-range planning, program strategy, business development, and key enterprise decision-making. Fostering a highly collaborative, roll-up-your-sleeves culture and be a mentor to team members. Collaborate cross-functionally with Research, Regulatory, CMC, Finance, Corporate Strategy, and Business Development teams. Engage with patient advocacy groups, external experts, consultants, and key stakeholders to inform development and portfolio strategies. Serve as a strategic thought partner to senior leadership on portfolio strategy, future growth opportunities including business development. What you’ll need to be successful: Bachelor’s degree required; MBA, PhD, PharmD, MD, or other advanced scientific/business degree preferred. 10+ years of experience within biotechnology or pharmaceutical industry across New Product Planning, Commercial Strategy, Portfolio Strategy, Marketing, Competitive Intelligence, or related functions. Extensive experience supporting late-stage development programs and contributing to commercialization or launch planning activities. Strong understanding of drug development and ability to integrate commercial insights into clinical and portfolio strategy discussions. Oncology and rare disease experience strongly preferred. Experience operating in innovative or first-in-class therapeutic settings where market development and indication-shaping strategies were required. Demonstrated ability to work effectively across highly matrixed, cross-functional organizations. Strong strategic thinking and analytical capabilities, with the ability to synthesize scientific, clinical, and market information into actionable business insights. Proven ability to influence without authority and build strong collaborative relationships across functions and organizational levels. Experience working closely with Global Program Team, patient advocacy organizations, and external stakeholders preferred. Strong communication and presentation skills, including the ability to engage senior leadership and translate complex information into clear strategic recommendations. Leadership mindset with the ability to operate strategically while remaining hands-on in a fast-paced, high-growth environment. Prior experience within oncology, precision medicine, platform biotechnology, or emerging biotechnology companies is a plus. Demonstrated use of AI tools in your current role and
responsibilities is required. Advanced or innovated use of AI is a strong plus Core Values Parabilis Medicines is a team of passionate pioneers who are trailblazing the future of precision medicine with the aim of making a meaningful difference in the lives of patients. The company is committed to promoting an inspiring and flourishing working environment for all employees across the business, in all departments, and driving innovation for patient benefit. Growth-Minded . We’re inventing a new class of medicines—one applicable to therapeutic targets that have been dreamt about, but always considered impossible to drug. Our work requires us to be curious, humble and adaptable. In(ter)dependent. We are fiercely independent as a leader in defying the limitations of current therapeutic modalities, and interdependent as a team as we work collaboratively to shift drug discovery paradigms and provide patients with better treatment options. Patient-focused. We are deeply focused on patient outcomes, and all energy in the company is focused on science as it translates to patient impact. All-In. We’re All-In on solving some of the hardest scientific challenges and delivering one of the most effective new classes of drugs in history. The base salary range for this position is $315,000-$345,000, depending on experience,
qualifications, and internal practices. Parabilis’s total
compensation package also includes an annual target
bonus, equity, and a comprehensive suite of competitive
benefits designed to support our employees’ overall well-being. As an equal opportunity employer, Parabilis Medicines values an inclusive workplace and welcomes applicants of all backgrounds and experiences. All qualified applicants will receive consideration for employment without discrimination on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability, or any other factors prohibited by law. 30 Acorn Park Drive | Cambridge, MA 02140 | www.parabilismed.com
