Director, CMC Formulation Development and Manufacturing

Requirements: Ph.D. in Pharmaceutics, Chemistry, Chemical Engineering or related discipline with a minimum of (12) years or M.S with a minimum of (15) years of development experience and demonstrated ability in leading cross-functional groups. Late phase and commercial experience are a plus. Demonstrated track record of success in delivering timely execution of DP and CMC activities ranging from preclinical, IND-enabling and NDA material supplies, through GMP clinical trial supplies and commercialization. Demonstrated expertise in small molecule formulation development (traditional oral solid dosage and enabling formulations such as ASD and HME is a plus), scale-up and manufacturing, and phase appropriate control strategy and specification development. Experience with analytical techniques for small molecules and oral solid dose products, with proficiency in UPLC/HPLC, dissolution, and solid-state characterization techniques such as DSC/TGA, PLM, XRPD and laser diffraction PSD method. Track records to interpretate the analytical data and application to support formulation development. Good understanding of physico-chemical properties of API, PK/PD correlation and develop the phase appropriate formulations Strong understanding of Quality systems including SOPs, manufacturing record review, batch release and disposition, Good Documentation Practices, cGMP data traceability, Deviations, and Change Management. Demonstrated knowledge and application of current industry and compendial standards and regulatory authority guidance and expectations, including ICH, FDA, MHRA, and EMA guidelines and USP-NF, Ph. Eur, BP, and JP compendia Experience in managing global CDMOs and reviewing documentation and ensuring proper guidelines are followed. Exceptional problem-solving skills and ability to quickly adapt and shift focus as needed Excellent interpersonal and communication skills for internal and external collaborations Ability to multi-task in a fast-paced dynamic environment while demonstrating a calm and positive attitude and a superior work ethic Excellent interpersonal communication and decision-making skills Able to travel domestic and internationally to oversee DP development and manufacturing at CDMOs All employees are expected to act with integrity and in full compliance with applicable laws, regulations, and IDEAYA policies, including IDEAYA’s Code of Conduct. Employees must demonstrate good judgement and ethical behavior in all business activities, maintain patient and product safety as a top priority, and report any suspected violations of law or Company policy through appropriate channels Total Rewards Along with our inspiring mission, and highly collaborative and inclusive environment, IDEAYA offers a competitive total rewards package that reflects our pay-for-performance philosophy where employees are eligible to be considered for merit-based salary increases, company discretionary short-term incentive plan participation, and company discretionary stock option awards (based on board approval). Our comprehensive

benefits package includes, but is not limited to, medical/dental/vision coverage (100% company paid for employees and 90% company paid for dependents), 401k, ESPP, and wellness programs. The expected salary range for

the role of Director, CMC Formulation Development and Manufacturing is $215,000 - $266,000. The final salary offered to a successful candidate will depend on several factors that may include but are not limited to the office location where this open position is located, the final candidates’ experience within their profession, experience in the disease areas we are striving to make an impact in as a company, length of time within the industry, educational background, and performance during the interview process. The Company complies with all laws respecting equal employment opportunities and does not discriminate against applicants with regard to any protected characteristic as defined by federal, state, and local law. This position requires you to work onsite in the office at the Company’s facilities for training & meetings, with work-from-home flexibility, and the Company requires that all employees working in its facilities be fully vaccinated (except as required by applicable law). Therefore, this position requires you to be fully vaccinated from COVID-19, subject to reasonable accommodations for medical or religious reasons, and/or as otherwise required by applicable law. The Company considers you fully vaccinated once 14 days have passed since you received either the second dose in a two-dose COVID-19 vaccine series or a single-dose COVID-19 vaccine. The vaccine must have been FDA approved, have emergency use authorization from the FDA, or, for persons fully vaccinated outside of the U.S., be listed for emergency use by the World Health Organization. IDEAYA is an equal opportunity employer. In accordance with applicable law, IDEAYA does not discriminate in hiring or otherwise in employment based on race, color, religion, sex, national origin, age, marital or veteran status, disability, sexual orientation, or any other legally protected status. EOE/AA/Vets. We are committed to providing reasonable accommodations to qualified individuals with disabilities. If you need assistance or an accommodation due to a disability, please get in touch with us at [email protected]. At IDEAYA we believe in the importance of on-site presence by all team members as an essential ingredient to effective collaboration. Our hybrid approach to work at IDEAYA includes all staff being on-site four days per week in the office, and one day per week working from home. IDEAYA Company Values: Passionate Commitment Fearless Innovation Courageous Integrity Respectful Teamwork Objective Decision-Making Empowered Accountability For more information, please see www.ideayabio.com California Job Applicant Privacy Notice

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