Controller

compensation expense, 409A valuation support, cap table integrity, and related financial statement disclosures) in partnership with the equity platform (Carta or equivalent) Design, implement, and maintain an internal control framework scaled for a high-growth tech company, balancing rigor with operational practicality as the company grows Lead audit readiness and serve as the primary point of contact for external auditors; drive clean, timely delivery of annual financial statement audits Manage federal, state, and local tax compliance in coordination with external advisors; lead R&D tax credit studies and other R&D-related tax matters, including Section 174 capitalization considerations Establish, document, and maintain accounting infrastructure, policies and procedures that meet institutional standards and support rigorous audit and regulatory scrutiny Evaluate and implement finance technology, including procure-to-pay and close management tools, to reduce manual effort, improve auditability, and strengthen data integrity at scale Own cash management, banking relationships, and treasury operations, including cash forecasting and liquidity monitoring appropriate for a venture-backed company at Profluent's stage

Qualifications Bachelor's degree in Accounting or Finance, active CPA license 10+ years of progressive accounting experience, with at least 3 years in a Controller or senior accounting leadership role, preferably within a Big 4 or similar environment Prior experience in a pre-IPO or high-growth venture-backed company environment required (e.g., biotech, tech) Demonstrated experience with NetSuite, including implementation, migration, or optimization (experience migrating from QuickBooks or similar legacy system strongly preferred) Hands-on experience designing and maintaining internal control frameworks Strong command of U.S. GAAP; ability to independently research and document technical accounting positions Experience managing external financial audits and serving as primary point of contact for auditors Preferences Experience with equity administration platforms (e.g., Carta) and ASC 718 accounting Familiarity with CRO accruals, R&D capitalization policy, R&D tax credits Experience with procure-to-pay platforms and ERP integrations (Coupa, Airbase, or similar) SOC 2 compliance experience What We Offer High-growth opportunity with meaningful impact on the future of protein design Competitive

compensation package with equity participation Comprehensive

benefits including health/dental/vision insurance Generous PTO policy and commitment to work-life balance Professional development opportunities in a cutting-edge field at the intersection of AI and biology Profluent Bio, Inc is an equal opportunity employer promoting diversity and inclusion in the workspace. We do not discriminate on the basis of race, color, religion, marital status, age, national origin, ancestry, physical or mental disability, medical conditions, veteran status, sexual orientation, gender (including gender identity and gender expression), sex (which includes pregnancy, childbirth, and breastfeeding), genetic information, taking or requesting statutorily protected leave, or any other basis protected by law. Work Authorization Requiremen t Applicants must have ongoing work authorization in the United States that does not require employer sponsorship. Sponsorship will not be provided now or at any time in the future for this position. Employment Eligibility Verification Legal authorization to work in the United States is required. In compliance with federal law, all persons hired must verify their identity and work eligibility and complete the required employment verification form upon hire. Hiring Salary Range $185,000 — $230,000 USD

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