About the role
About Us We are developing potentially best in class therapies for patients living with severe autoimmune diseases. Our lead antibody, claseprubart (DNTH103), is purposefully engineered with extended half-life, improved potency, and high selectivity for only the active C1s complement protein that drives disease pathology – enabling less frequent and more convenient self-administered subcutaneous injections. Our second clinical candidate, DNTH212 is a first and potentially best in class, bifunctional inhibitor that targets clinically validated and complementary disease modifying mechanisms, Type 1 IFN suppression and B cell modulation – enabling potential for improved clinical outcomes and patient friendly convenient, self-administered subcutaneous injections. To learn more, please visit www.dianthustx.com and follow us on LinkedIn .
About
the Role Dianthus Therapeutics is seeking an accomplished and strategic Executive Director, Clinical Data Management to lead the development, execution, and long-term evolution of our Clinical Data Management function. Reporting to the Senior Vice President, Clinical Development Operations, this individual will establish the vision, organizational structure, systems, processes, and operating model needed to support a growing clinical development portfolio. As the functional leader for Clinical Data Management, the Executive Director will be responsible for building and scaling the department, developing talent, establishing SOPs and governance frameworks, and ensuring the delivery of high-quality, regulatory-compliant clinical data to support critical business decisions, regulatory submissions, and future commercialization efforts. This is a highly visible leadership role requiring both strategic and operational expertise. While responsible for setting departmental direction and building organizational capabilities, the Executive Director will also remain actively engaged in study-level execution, vendor oversight, and cross-functional collaboration in a fast-paced biotechnology environment. We are building a culture of individuals who hold our core principles at the center of our operations, with the goal to elevate the care of our patients’ lives. We are open to you working remotely. Key
