About the role
GT Biosciences is seeking a detail-oriented Contract In Vivo Research Associate / Scientist to support studies in mouse models. Key
responsibilities include performing intravenous (IV; tail vein), intraperitoneal (IP), subcutaneous Injection (SC/Subq) dosing procedures; animal handling and monitoring; blood and tissue collection; organ harvesting; and tissue processing (slicing) for downstream analyses. The ideal candidate will have demonstrated expertise in rodent in vivo techniques and experience preparing and sectioning tissues for histological, molecular, or cellular characterization. This is a contract, onsite position based in the Cambridge, MA area and will involve work at local vivarium and CRO facilities, including Charles River Laboratories. Time commitment: Approximately 5–10 hours per week, with scheduling dependent on study timelines and animal facility availability. Work may be clustered around dosing days, study endpoints, and tissue collection windows.
Responsibilities Independently perform rodent dosing procedures, including intravenous (tail vein), intraperitoneal, subcutaneous, and other routes of administration in accordance with study protocols. Support the execution of preclinical studies in mouse and rat models while ensuring compliance with approved IACUC protocols and institutional animal care guidelines. Perform animal handling, restraint, clinical observations, body weight measurements, and general study support activities. Perform transcardial perfusions and tissue fixation procedures to support histology, immunohistochemistry, and other downstream tissue-based assays. Conduct blood collection procedures using appropriate techniques, including terminal and non-terminal sampling methods. Harvest and collect tissues at designated study endpoints, including brain, spleen, liver, lung, kidney, bone marrow, lymph nodes, tumors, and other organs as required. Process tissues for downstream analyses, including weighing, dissection, sectioning, dissociation, fixation, cryopreservation, embedding, and histological preparation. Prepare tissue samples for flow cytometry, molecular biology, histopathology, immunohistochemistry, and other analytical assays. Maintain accurate and organized experimental records, study documentation, and data entry in accordance with company standards and regulatory
