Crinetics is a pharmaceutical company based in San Diego, California, developing much-needed therapies for people with endocrine diseases and endocrine-related tumors. We were founded by a dedicated team of scientists with the simple belief that better therapies developed from rigorous innovation can lead to better lives. Our work continues to make a real difference in the lives of patients. We have a prolific discovery engine and a robust preclinical and clinical development pipeline. We are driven by science with a patient-centric and team-oriented culture. Crinetics is known for its inclusive workplace culture. We are also a dog-friendly workplace. This is an exciting time to join Crinetics as we shape our organization into the world’s premier fully-integrated endocrine company from discovery to patients. Join our team as we transform the lives of others. Position Summary: This position will lead several early or one late-stage development programs and contribute to portfolio strategy for other programs within a growing preclinical and clinical stage pipeline covering endocrinology and endocrine related tumors. The Director, Global Product Leader is responsible for the strategic leadership of a Global Product Team, overseeing strategic planning, decision making, and resource/budget management and prioritization across development, regulatory, CMC, operations, and business functions to ensure rapid, efficient, and successful progression of the program(s). This role will be responsible for the full lifecycle management of their product and ensure that strategic plans and goals are met. The Global Product Leader will ensure cross-functional and organizational readiness for regulatory filings, IND applications, and planning through commercial launch activities, depending on the development stage of the asset. All Global Product Leaders have regular and direct communication with the CEO and are expected to be the CEO’s direct delegate of authority for the successful progression of candidates through development to successful commercial launch and lifecycle management. They are also expected to represent their products effectively to the board of directors, key scientific and medical leaders, and investors. Essential Job Functions and
Responsibilities: These may include but are not limited to: Lead cross-functional Global Product Team(s), partnering with the Project Manager and functional leaders from development, regulatory, CMC, operations, commercial and other business functions. Have clear ownership of progressing the program forward and be the primary point of contact for the CEO and executive leadership on strategy, risks and execution progress. Contribute to corporate strategic initiatives including portfolio-level strategy for entry and expansion into oncology and contribution to other oncology programs at Crinetics. Accountable for building strategic and coordinated product development plans, aligned with program vision, business objectives and key results and are differentiated from competitor products. To include creation and integration of clinical development plans, lifecycle strategies and regulatory submissions. Drive
the team to out-of-box thinking, effectively run/mitigate/communicate risk, make decisions, and handle conflict and change. Challenge assumptions, timelines and expenses at program level, pressure tests plans, create alternative scenarios to enable strategic and operational agility. Manage prioritization of program team activities to enhance program value. Drive team objective and goal setting, prioritization, and adherence to plan and strategy. Lead and communicate the product development strategy at governance meetings, accountable for aligning with executive leadership and for communicating with external collaborators. Partner with functional heads across all key product development areas, including Discovery, Development, Regulatory, CMC, and Commercial, to ensure strategic alignment and achievement of program deliverables. Responsible for maintaining a high degree of GPT effectiveness through collaboration, influence, and, as necessary, coaching and mentoring of cross-functional team members. Maintain strong industry awareness and knowledge to ensure that product plans reflect current scientific/medical developments and regulatory/commercial environment. Support execution of company sponsored publication plans to ensure timely production of manuscripts and other communication tools. Ensure presentations and other product communications are clear and effective. Ensure Product and Sub-team readiness for regulatory filings and commercial launch readiness Contribute to corporate strategic initiatives including portfolio-level strategy discussions. Other duties as assigned. Education and Experience: Required: Demonstrated experience and leadership in product development in oncology, including regulatory filings (INDs, BLA/NDA), DC nomination, and/or life cycle management. Bachelor’s degree in a science related field required. PhD., MD, MPH, MS, or other advanced degree in scientific field preferred. Minimum of 12 years related experience in the biotech or pharmaceutical industry, with strong working knowledge of drug development. 8 years of demonstrated supervisory experience. Strong understanding of comprehensive drug development process with a focus on early to mid-stage product development. Demonstrated cross functional ability to lead and react to different situations and emotions of others, including customers, employees, and all others; high EQ. Ability to inspire, motivate, and effectively lead diverse groups of people and teams. A proactive and strategic thinker, with strong decision-making skills. Excellent business acumen with demonstrated ability to align teams to corporate strategy to achieve business and project objectives. Proven ability to successfully lead and manage effectively across a matrix organization with multiple stakeholders and constituents. Strong leadership and communication skills (including presentation skills) with success in influencing all levels cross-functionally. Highly collaborative with outstanding relationship building skills. Highly self-motivated and able to independently and effectively drive for results. Enthusiasm for working in a dynamic environment with a sense of urgency and aggressive timelines. Demonstrates a creative and entrepreneurial mindset. Strong ability to influence cross-functionally within the organization without direct authority. Physical Demands and Work Environment: Physical Activities: On a continuous basis, sit at desk for a long period of time; intermittently answer telephone and write or use a keyboard to communicate through written means. Some walking and lifting up to 25 lbs. may be required. The noise level in the work environment is typically low to moderate. The physical demands described above are representative of those that must be met by an employee to successfully perform the essential functions and
responsibilities of this job. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions and
responsibilities. Travel: Position can be local or remote based. If remote, you will be required to come to the office on an as needed basis. You may be required to travel for up to 25% of your time. The Anticipated Base Salary Range: In addition to your base pay, our total rewards program consists of a discretionary annual target
bonus, stock options, ESPP, and 401k match. We also provide top-notch health insurance plans for employees (and their families) to include medical, dental, vision and basic life insurance, 20 days of PTO, 10 paid holidays, and a winter company shutdown. The final salary offered to a successful candidate will be dependent on several factors that may include but are not limited to the type and length of experience and education. Crinetics Pharmaceuticals is a multi-state employer, and this salary range may not reflect positions that work in other states. Your recruiter can share more about the specific salary range during the hiring process. Equal Opportunity Employer: Crinetics is proud to be an Equal Opportunity Employer. We provide equal employment opportunities to all employees and employment applicants without regard to unlawful considerations of sex, sexual orientation, gender (including gender identity and/or expression), pregnancy, race, color, creed, national or ethnic origin, citizenship status, religion or similar philosophical beliefs, disability, marital and civil union status, age, genetic information, veteran status or any personal attribute or characteristic that is protected by applicable local, state or federal laws. Salary Range The salary range for this position is: $187000 - $233000. In addition to your base pay, our total rewards program consists of a discretionary annual target
bonus, stock options, ESPP, and 401k match. We also provide top-notch health insurance plans for employees (and their families) to include medical, dental, vision and basic life insurance, 20 days of PTO, 10 paid holidays, and a winter company shutdown. Thank you for considering Crinetics Pharmaceuticals as your potential employer! Explore job opportunities and discover how you too can make a real impact as we tackle big challenges in endocrinology. Crinetics Pharmaceuticals is a global, clinical-stage pharmaceutical company focused on the discovery, development, and commercialization of the next generation of therapeutics for patients with endocrine and endocrine-rooted diseases. Founded by an innovative team of scientists with a track record of successful drug discovery and development, we’re fueled by collaboration, curiosity, and empathy. We have a prolific discovery engine and robust pipeline across preclinical and clinical development that are purposefully designed to meet the needs of patients, empowering them to live life beyond their condition. Join our team on our mission to improve patients’ lives and transform the treatment paradigm in areas of serious unmet need.
