Sr. Medical Director, Clinical Development

Responsibilities: Provide medical leadership for various programs from first-in-human studies through registrational studies. Late-stage development experience is preferrable Formulate study designs, lead protocol development, partner with internal cross-functional teams in study start-up activities, and collaborate with clinical investigators, key external experts, and Health Authorities Participate in direct, hands-on involvement in all aspects of study conduct clinical activities, working with clinical operations, including data review, analysis, and reporting that conform to the ethical, safety, and quality standards of Cabaletta, GCP, and Health Authorities Become an expert and remain current in the relevant therapeutic areas and in the field of cell and gene therapy through review of the scientific literature, interactions with key external experts, and attendance at relevant scientific meetings Actively contribute during Health Authority interactions Review available preclinical data that could inform the design of future clinical trials Present at site evaluation and site initiation visits as applicable In partnership with relevant cross-functional team members, actively engage in the preparation of Clinical Study Reports, Annual Reports and other safety reports, Health Authority pre-meeting packages, Investigator Brochures, periodic clinical reports, and BLA submission documents Collaborating with cross-functional groups, formulate publication strategy including active participation in authoring, preparation and review of manuscripts, conference abstracts and presentations and other external presentations of clinical data

Qualifications: M.D., M.D./Ph.D. degree or equivalent required Board Certification, Board Eligibility, or clinical experience in the field of Rheumatology and/or Immunology highly desirable 7+ years of experience in clinical research, including the design and execution of complex clinical trials, with a pharmaceutical or biotech company Experience with or exposure to the development of adoptive cell therapies or biologic therapies is desirable Experience with Health Authority interactions and submission of clinical regulatory documents is desirable Strong written and verbal communication skills; ability to easily engage with investigators and key external experts; and ability to effectively present at conferences, advisory meetings, and other public for a Engaged, hands-on, independent, and goal-oriented mentality; willingness to work in highly dynamic work environment Ability to multi-task and willingness to flexibly contribute simultaneously to multiple facets of drug development; willingness to learn new therapeutic areas and technologies Self-motivated, innovative, and critical thinker with strong commitment to follow up on action items; strong organizational, analytical, and problem-solving skills Strong influencing skills and ability to create a clear sense of direction Thrives in a fast-paced small company environment and able to adjust priorities and workload based upon changing needs Comfortable with ambiguity and ability to define processes and procedures from scratch Strong team orientation and passion for continuous self-development Ability and willingness to travel as required Our name – Cabaletta – is derived from the operatic term that represents a rapid, repetitive, and technically challenging section of an operatic aria, designed to showcase the skills of the lead singer. Analogously, Cabaletta Bio strives to achieve rapid and repetitive product development, building on our indication prioritization and biologic platform that targets the driver of specific autoimmune diseases without the need for long-term immunosuppression. For more information, please visit https://www.cabalettabio.com/join-our-crew Our most important asset is our people, and we offer competitive

benefits, PTO, and stock option plans. Cabaletta Bio is an equal opportunity employer. We do not discriminate on the basis of race, color, gender, gender identity, sexual orientation, age, religion, national or ethnic origin, disability, protected veteran status or any other basis protected by applicable law. Cabaletta Bio, Inc. does not accept unsolicited resumes from recruiters, employment agencies, or staffing firms. To conduct business with Cabaletta, a Master Services Agreement (MSA) must be executed and confirmed prior to submitting any information relating to a potential candidate. Without a signed MSA, Cabaletta shall not be responsible to any individual or entity for any payment relating to any form of fee or

compensation. And, if a resume or candidate is submitted by a recruiter, an employment agency, or a staffing firm without a fully executed MSA, Cabaletta has the unrestricted right to pursue and hire any of those candidate(s) without any legal or financial responsibility to the recruiter, agency, and/or firm. #LI-REMOTE Apply for this job First name Last name Email address Location Phone number Resume Attach resume Attach another file Attach file Add another What is your Linkedin Profile URL? Are you authorized to work in the United States? Yes No Will you now or in the future require sponsorship for employment visa status (e.g. H-1B status)? Yes No What is the highest level of education you’ve obtained? No answer GED or Equivalent High School Some College College - Associates College - Bachelor of Arts College - Bachelor of Fine Arts College - Bachelor of Science College - Master of Arts College - Master of Science College - Master of Fine Arts College - Master of Business Administration College - Doctorate Medical Doctor Other Linkedin url Should be {http://www.linkedin.com/pub/[member-name/]x/y/z} or {http://www.linkedin.com/in/string} © 2014-2026 TriNet Group, Inc. All rights reserved. Privacy Policy

A meeting lands on your calendar

If they’re a yes, I book the chat. You show up — that’s the whole job-hunt.