About the role
JOB SUMMARY Iambic Therapeutics is seeking a Director of Clinical Supply Chain within CMC function to lead end-to-end clinical supply strategy and execution for small molecule programs from first-in-human through clinical phases. This role will develop and execute integrated supply plans, oversee packaging/labeling and global distribution, and ensure uninterrupted investigational product supply to clinical sites while minimizing waste and controlling cost. The successful candidate will partner closely with Clinical Operations, Regulatory, Quality, Project Management, and CMC technical teams to align forecasts and manufacturing schedules, manage vendor performance, maintain inspection-ready documentation, and establish fit-for-purpose IRT/RTSM
requirements to enable reliable, patient-ready clinical supply execution. Preferred location is in San Diego, CA KEY
RESPONSIBILITIES Serve as the clinical supply chain lead in a cross-functional matrix team, defining and driving execution of clinical supply strategies aligned with protocol
requirements and program timelines. Develop and maintain integrated demand forecasts, enrollment scenarios, and inventory/resupply strategies to ensure uninterrupted IP/IMP supply to depots and clinical sites while minimizing waste and write-offs. Plan and oversee packaging and labeling operations with CPO partners, including label content coordination and cross-functional review/approval workflows in alignment with regulatory
requirements. Own logistics strategy across the networks (DS/DP CDMOs, packaging/labeling sites, depots, and global clinical sites), including shipment execution and import/export coordination. Oversee depot operations including inventory oversight, drug accountability, returns, reconciliation, and destruction. Provide strategic direction for clinical supply planning to establish IRT/RTSM