Machine Learning Research Scientist

San Francisco, CA
Full-time
Visa Sponsorship

About the role

About Blank Bio

Blank Bio is an applied AI research lab focused on increasing the success rates of clinical trials. We do this by training RNA foundation models that learn the patterns that shape disease progression and patient response to treatment. We aim to help pharma make more informed decisions in clinical trials by capturing the biology that makes each patient’s tumour unique. 

We’re a technical team of AI scientists and engineers from companies including Recursion, Deep Genomics, DeepMind, and Amazon, and institutions including Memorial Sloan Kettering Cancer Centre, Stanford, and the Vector Institute.

The Role

As an ML research scientist, you’ll design novel ML methods and develop benchmarks that reflect clinically relevant biology. As an early-stage startup, we move fast, work across disciplines, and embrace ambiguity. We’re looking for people who thrive in dynamic environments, are eager to take ownership, and want to help define both the science and the culture of the company.

Responsibilities

  • Design and prototype new ML methods (representation learning, generative modeling, contrastive pretraining) for RNA biology.
  • Develop benchmarks and evaluation frameworks for tasks spanning diagnostics, patient stratification, biomarker discovery, and more
  • Analyze large-scale sequencing datasets (bulk RNA-seq, single-cell, long-read) to inform model development and evaluation.

Qualifications

Must-haves

  • PhD (or equivalent experience) in Machine Learning, Computational Biology, or related fields.
  • Demonstrated track record in ML research (publications, impactful projects, or deployed systems).
  • Expertise in representation learning, and/or large-scale sequence modeling.
  • Ability to independently design and execute research projects.

Nice-to-haves

  • Familiarity with transcriptomics, RNA biology, or other -omics data.
  • Experience developing benchmarks for biological or clinical ML tasks.
  • Prior collaboration with clinical researchers, diagnostic developers, or biomarker discovery teams.
  • Previous work in an early-stage, fast-paced environment.

Compensation & Benefits

  • Competitive salary and meaningful early-stage equity.
  • Comprehensive health, dental, and vision coverage.
  • Generous vacation and parental leave policies

About Blank Bio

RNA intelligence for precision medicine

Other roles at Blank Bio

Interested?

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Job details

Salary

$150,000 - $250,000

Equity

0.2% - 1%

Location

San Francisco, CA

Experience

0+ years

Company

NameBlank Bio
IndustryTherapeutics
Team Size6

Funding

Total raised

$7.7M

Last stage

Seed

Investors

Y Combinator
SSignalFire
DDefine Ventures
Leonis Capital
Ripple Ventures

Founders

RS

Ruian (Ian) Shi

Co-Founder

Jonny Hsu

Jonny Hsu

Co-Founder & CEO

LinkedIn
Ian Shi

Ian Shi

LinkedIn
Philip Fradkin

Philip Fradkin

Co-Founder

LinkedIn

What happens next.

No applications, no recruiter spam. Just the intro.

01

Confirm the fit

A few questions to make sure this role is the right shape for you. Two minutes.

02

I pitch you to the company

I write the intro, send it to the founder, and handle the back-and-forth.

03

A meeting lands on your calendar

If they’re a yes, I book the chat. You show up — that’s the whole job-hunt.