Job Application for Senior Bioinformatics Scientist, Oncology Applications at Ultima Genomics Senior Bioinformatics Scientist, Oncology Applications Remote US Apply Rapidly Growing Life Sciences Technology Company Ultima Genomics is a rapidly growing company that is developing ground-breaking genomics technologies. Our mission is to continuously drive the scale of genomic information to enable unprecedented advances in biology and improvements in human health. We have developed a foundational new approach to sequencing at scale that overcomes limitations due to the high costs of current technologies. We are well-funded and have raised approximately $600 million from global top-tier investors. Our team brings together unique and diverse expertise across multiple disciplines, from healthcare and life sciences, to engineering, to technology and software and beyond. We are a collaborative group, including successful entrepreneurs, chemists, hardware and software engineers, genomics and biotechnology experts, molecular and computational biologists, software and algorithm experts, and operations and commercial leaders. Join us to develop and commercialize technologies that unleash the power of genomics at scale and empower the future of human health. We are looking for a highly motivated Senior Bioinformatics Scientist to join our Oncology Applications team! As a Senior Bioinformatics Scientist, you will develop and apply computational methods for analyzing next-generation sequencing (NGS) data generated on Ultima’s platform. This role will involve building robust pipelines, developing novel algorithms, collaborating cross-functionally with molecular biology, software engineering, and product teams, and driving insights from complex genomic datasets, with a focus on growing Oncology Applications. This position is ideal for someone who thrives in a dynamic, fast-paced environment and can effectively balance multiple high-impact projects. In addition to core R&D
responsibilities, you will contribute to external-facing scientific communications and support collaborations with customers and partners. How You’ll Contribute Develop, optimize, and maintain scalable bioinformatics pipelines for NGS data analysis such as WGS, WES, RNA-seq, and single-cell Design and implement novel algorithms for secondary and tertiary NGS analysis tailored to Ultima’s sequencing chemistry Lead and execute multiple projects simultaneously, effectively prioritizing deliverables in alignment with evolving company goals Perform benchmarking and validation studies Analyze large-scale genomic datasets and generate actionable insights for internal R&D, product development, and external collaborators Collaborate closely with wet-lab scientists, software engineers, and product teams to translate experimental results into improved workflows and tools Support external collaborations by preparing technical analyses, reports, presentations, and data summaries for customers, partners, and conferences Contribute to scientific publications, application notes, white papers, and other external communication materials as needed Participate in customer-facing discussions to explain data analysis approaches, performance metrics, and platform capabilities Document methods clearly and communicate findings effectively to both technical and non-technical audiences Stay current with emerging technologies and advances in genomics, computational biology, machine learning, and cancer biology Other duties as assigned
Qualifications, Skills, Knowledge & Abilities PhD in Bioinformatics, Computational Biology, Genomics, Computer Science, or related field; or MS with significant industry experience PhD with 2+ years or MS with 5+ years of hands-on experience analyzing NGS data is required Strong programming skills in Python and/or C++ Experience with common bioinformatics and somatic variant calling tools such as BWA, minimap2, GATK, samtools Proficiency in Linux/Unix environments and workflow management systems (Nextflow, Snakemake, WDL) Experience working with large datasets in cloud environments (AWS, GCP) Solid understanding of genomics and cancer biology Strong statistical and data analysis skills Demonstrated ability to manage multiple concurrent priorities and deliver high-quality work under tight timelines Knowledge of machine learning approaches applied to genomics Clear and confident communicator, comfortable in external-facing settings Experience in regulated environments (CLIA, CAP) is a plus Thrive in a fast-paced, startup environment with evolving priorities Demonstrated scientific rigor and analytical thinking High ownership, accountability, and bias toward action Collaborative mindset with cross-functional agility At Ultima Genomics, your base pay is one part of your total
compensation package. This role pays between $115,000 and $145,000, if performed in the US, and your actual base pay will depend on your skills,
qualifications, experience, and location. Please note that the
compensation details listed in US role postings reflect the base salary only, and do not include
bonus, equity, or
benefits. This role is also eligible for a competitive
benefits package that includes: medical, dental, vision, life, and disability insurance; 401(k) retirement plan; flexible spending & health savings account; paid holidays; paid time off; employee assistance program; and other company
benefits. #LI-Remote Ultima Genomics is proud to be an equal opportunity workplace and is an affirmative action employer. We provide equal employment opportunity for all applicants and employees. We do not discriminate on the basis of race, color, religion, sex (including pregnancy, childbirth, or related medical conditions), gender identity, gender expression, national origin, ancestry, citizenship, age, physical or mental disability, military or veteran status, marital status, domestic partner status, sexual orientation, genetic information, or any other basis protected by applicable laws. See also Ultima Genomics’ EEO Policy and Know Your Rights . If you have a disability or special need that requires accommodation, please let us know by contacting [email protected] . Create a Job Alert Interested in building your career at Ultima Genomics? Get future opportunities sent straight to your email. Create alert Apply for this job * indicates a required field Autofill with MyGreenhouse First Name * Last Name * Email * Phone Country Phone Resume/CV * Attach Attach Enter manually Enter manually Accepted file types: pdf, doc, docx, txt, rtf Cover Letter Attach Attach Enter manually Enter manually Accepted file types: pdf, doc, docx, txt, rtf LinkedIn Profile Where did you hear about this position at Ultima Genomics? * Select... What sequencing platforms have you worked with for oncology applications (e.g., WGS, WES, ctDNA, tumor-normal), and how has the choice of platform — including its chemistry and error profile — affected your downstream somatic variant calling or CNV analysis decisions? * What's the largest dataset (in terms of samples or raw data volume) you've processed? What were the computational constraints and how did you handle them? * What does 'production-ready' mean to you for a bioinformatics analysis pipeline — particularly in contexts where results may inform clinical decisions or external collaborations? Walk us through something you've done to harden a research pipeline toward that standard." * What's a widely accepted practice in cancer genomics or somatic variant analysis — a filtering heuristic, a tool default, a benchmarking standard — that you're skeptical of or have pushed back on in your own work? What drove that skepticism? * Will you now or in the future require visa sponsorship to work in the US? * Select... If you do require visa sponsorship, please provide details including type and expiration of current visa. If you were referred by an Ultima Genomics employee, please list their name. Where are you located (City & State)? * Voluntary Self-Identification For government reporting purposes, we ask candidates to respond to the below self-identification survey. Completion of the form is entirely voluntary. Whatever your decision, it will not be considered in the hiring process or thereafter. Any information that you do provide will be recorded and maintained in a confidential file. As set forth in Ultima Genomics’s Equal Employment Opportunity policy, we do not discriminate on the basis of any protected group status under any applicable law. Gender Select... Are you Hispanic/Latino? Select... Race & Ethnicity Definitions If you believe you belong to any of the categories of protected veterans listed below, please indicate by making the appropriate selection. As a government contractor subject to the Vietnam Era Veterans Readjustment Assistance Act (VEVRAA), we request this information in order to measure the effectiveness of the outreach and positive recruitment efforts we undertake pursuant to VEVRAA. Classification of protected categories is as follows: A "disabled veteran" is one of the following: a veteran of the U.S. military, ground, naval or air service who is entitled to
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Field Service Engineer II, UAE
Field Service Engineer I, Development Program
Senior Linux Systems Engineer
Senior Software and Algorithm Engineer
Sales Manager, Genomic Tools & Applications, NorCal/Pacific Northwest
Salary
$115,000 - $115,000
Location
Remote
Experience
5+ years
Total raised
$700.0M
Investors
No applications, no recruiter spam. Just the intro.
A few questions to make sure this role is the right shape for you. Two minutes.
I write the intro, send it to the founder, and handle the back-and-forth.
If they’re a yes, I book the chat. You show up — that’s the whole job-hunt.