Head of Engineering

New York City
Full-time
Visa Sponsorship

About the role

About Argon

At Argon, we’re on a mission to transform how life-changing therapies are brought to patients. We’re building the AI operating system for the biopharma companies of the future, where humans and AIs work alongside one another to handle complex research, writing, and coordination workflows.

We’re honored to enable the next generation of scientists and pharma companies to bring life-saving therapies to market faster and more efficiently. We value kindness, intensity, direct communication, intellectual honesty, and grit. Join us if you want to be productive, ship, and help build a generational company.

We are an in-person company with offices in NYC. For non-NYC residents, we are happy to help cover moving and related expenses.

Why this role

If you’re excited about building a high-velocity engineering culture, designing a robust platform that will power the future of life sciences work, and pushing the forefront of AI products that accelerate the delivery of life-saving therapies, this role is for you. This is a high ownership role with real decision making authority, and comes with major equity upside.

Velocity is our advantage. Your north star will be compressing the build-ship-feedback-iterate loop without sacrificing product quality. This role has:

  • High ownership & autonomy
  • Frontier technical challenges
  • Equity upside
  • Blend of IC & manager time

You’ll have the unique opportunity to help set our engineering culture and systems, so that we minimize time to ship and time spent revisiting code. This is a hands-on leadership role: you will design, code, and spin up systems and new architectures, while shaping our organization and how we operate as a team.

What you bring

  • 8+ years of professional software engineering experience, with hands on coding experience in your most recent role.
  • Prior roles such as Principal/Staff/Senior Engineer, Tech Lead/Tech Lead Manager, Engineering Manager (hands-on), or Head of Engineering at Series B - FAANG companies.
  • Proven owner of engineering velocity and SDLC: you run lightweight planning/retros, track lead time/MTTR/change failure rate, drive multiple projects in parallel, keep tight loops with Product/Design/Ops—and raise the bar on code quality, testing, reviews, and release discipline without slowing flow.
  • Reliability at speed: deep experience with asynchronous patterns (queues, DLQs, idempotency, backoff/retry, replay, concurrency/eventual consistency), plus pragmatic CI/CD, observability (tracing/metrics/logging), SLOs/alerting, incident response, infra-as-code, and solid security basics.
  • Track record of shipping distributed systems at high-growth teams; you’ve made pragmatic, opinionated platform calls that improved developer speed and product reliability.
  • Deep experience with modern typed backends (one or more of: Node/TypeScript, Python, Go), PostgreSQL, and building asynchronous workflows with concurrency and eventual consistency.
  • Fluency with AWS and Kubernetes (SQS/SNS, S3, IAM, VPC) and systems-level concerns (observability, CI/CD, reliability engineering, security basics).
  • Strong database and data modeling instincts; you’ve tuned queries, managed migrations, and built for correctness and performance.
  • Hyper-communicative and detail-oriented; you write clearly, plan carefully, and keep stakeholders aligned without process bloat.
  • Care deeply about code quality and developer ergonomics; you set standards and hold the line through reviews, tooling, and mentorship.

Nice to have

  • Experience with React/Next.js and building intuitive, high-quality UIs.
  • AI-native product experience: prompt engineering, LLM orchestration, retrieval/re-ranking, evaluation frameworks.
  • Product sense and user empathy; you balance shipping fast with building the right abstractions and great UX.
  • Data and pipeline experience (ingestion, indexing, ETL/ELT, streaming).
  • Prior Head of Engineering/Tech Lead Manager experience; ex-founder or founding engineer background.

Compensation

  • $200,000-$350,000 base salary with 1%-5% equity

About Argon AI, Inc.

Argon AI is a platform where biopharma and life sciences professionals can execute complex and data driven workflows using natural language. We help professionals get thorough answers to questions about clinical trials, existing treatments, healthcare landscape, and the competitive market in minutes rather than months.

Prior to starting Argon, Samy was responsible for Flatiron Health’s (Roche) first data analytics project which eventually led to the start of the Flatiron Services business unit. There, he saw first-hand the heavily manual process that biopharma companies struggle through to get the insights they need to drive forward their drug development programs. He also helped close over $6M+ in ARR and is an expert in enterprise pharma sales.

Cyrus previously led engineering teams and built 0 to 1 across pre-seed and unicorn startups, managed mission-critical trade generation systems at Bridgewater, and held AI advisory roles at various startups. Cyrus has a duel degree in EE and CS from USC.

Breakthroughs in AI present an opportunity to reinvent biopharma and life science workflows to reduce the time and cost of bringing treatments to patients where delays in bringing a drug to market can cost a pharma company $3M / day.

Other roles at Argon AI, Inc.

Interested?

Let me introduce you to the founders.

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Job details

Salary

$200,000 - $350,000

Equity

1% - 5%

Location

New York City

Experience

6+ years

Company

NameArgon AI, Inc.
Team Size2

Funding

Total raised

$12M

Last stage

Seed

Investors

Crosslink Capital
WWireframe Ventures
Y Combinator
Pioneer Fund

Founders

Samy Danesh

Samy Danesh

LinkedIn
BD

Benedict Dohmen

Founder

SL

Santiago Lampo

Founder

Cyrus Jia

Cyrus Jia

LinkedIn

What happens next.

No applications, no recruiter spam. Just the intro.

01

Confirm the fit

A few questions to make sure this role is the right shape for you. Two minutes.

02

I pitch you to the company

I write the intro, send it to the founder, and handle the back-and-forth.

03

A meeting lands on your calendar

If they’re a yes, I book the chat. You show up — that’s the whole job-hunt.